SETD2 Antikörper
Kurzübersicht für SETD2 Antikörper (ABIN6290482)
Target
Alle SETD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human SETD2
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Isotyp
- IgG
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Applikationshinweise
- WB 1:200 - 1:500
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Kommentare
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Ubiquitously expressed
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- SETD2 (SET Domain Containing 2 (SETD2))
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Andere Bezeichnung
- SETD2
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Hintergrund
- Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
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Molekulargewicht
- 287.597 kDa
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Gen-ID
- 29072
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UniProt
- Q9BYW2
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Pathways
- Tube Formation
Target
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