WISP1 Antikörper (C-Term)
Kurzübersicht für WISP1 Antikörper (C-Term) (ABIN6266028)
Target
Alle WISP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- WISP1 Antibody detects endogenous levels of total WISP1.
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Homologie
- Rabbit
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human WISP1, corresponding to a region within C-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
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Andere Bezeichnung
- WISP1
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Hintergrund
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Description: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Gene: WISP1
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Molekulargewicht
- 40 kDa
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Gen-ID
- 8840
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UniProt
- O95388
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Pathways
- WNT Signalweg, Growth Factor Binding
Target
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