TCTN1 Antikörper (N-Term)

Produktnummer ABIN6265507

Dieses Anti-TCTN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TCTN1 in WB und IHC. Geeignet für Ratte, Human und Maus.

Kurzübersicht für TCTN1 Antikörper (N-Term) (ABIN6265507)

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCTN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TCTN1 Antikörper

Bindungsspezifität: N-Term

Spezifität: TCTN1 Antibody detects endogenous levels of total TCTN1.

Homologie: Pig

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TCTN1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TCTN1

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Andere Bezeichnung: TCTN1

Hintergrund:

Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).

Gene: TCTN1

Molekulargewicht: 55-64kDa

Gen-ID: 79600

UniProt: Q2MV58

Pathways: Tube Formation