SMAD2 Antikörper (C-Term)
Kurzübersicht für SMAD2 Antikörper (C-Term) (ABIN6265170)
Target
Alle SMAD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Smad2 Antibody detects endogenous levels of total Smad2.
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Homologie
- Zebrafish,Bovine,Sheep,Rabbit,Dog,Xenopus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Smad2, corresponding to a region within C-terminal amino acids.
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Isotyp
- IgG
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anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3G9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) antibodySMAD2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer423), (pSer425), (pSer465), (pSer467) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibodySMAD2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4D10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer467) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pThr183), (pThr221) antibodySMAD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibodySMAD2 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2D7 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 27-172) antibodySMAD2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IP Wirt: Maus Monoclonal 48-MAD2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 94-112), (N-Term) antibodySMAD2 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
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Andere Bezeichnung
- SMAD2
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Hintergrund
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Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Gene: SMAD2
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Molekulargewicht
- 58kDa
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Gen-ID
- 4087
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UniProt
- Q15796
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Pathways
- Zellzyklus, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
Target
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