RAB11B Antikörper (C-Term)

Produktnummer ABIN6264548

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAB11B in WB, ELISA, IHC, IF und ICC. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für RAB11B Antikörper (C-Term) (ABIN6264548)

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB11B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-RAB11B Antikörper

Bindungsspezifität: C-Term

Spezifität: Rab11B Antibody detects endogenous levels of total Rab11B.

Homologie: Pig,Bovine,Sheep,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Rab11B, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RAB11B

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Andere Bezeichnung: RAB11B

Hintergrund:

Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.

Gene: RAB11B

Molekulargewicht: 28kDa

Gen-ID: 9230

UniProt: Q15907

Pathways: Hormone Transport, Carbohydrate Homeostasis