Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) Antikörper

Details zu Produkt Nr. ABIN6263716
Antigen
  • BXR
  • ONR1
  • PAR
  • PAR1
  • PAR2
  • PARq
  • PRR
  • PXR
  • SAR
  • SXR
  • PXR.1
  • PXR.2
  • PXR1
  • mPXR
  • bxr
  • nr1i2
  • onr1
  • xonr1
  • nuclear receptor subfamily 1 group I member 2
  • nuclear receptor subfamily 1, group I, member 2
  • nuclear receptor subfamily 1 group I member 2 S homeolog
  • NR1I2
  • Nr1i2
  • nr1i2.S
  • nr1i2
Reaktivität
Human, Maus, Ratte (Rattus)
120
60
58
2
2
2
2
2
1
1
1
Wirt
Kaninchen
119
14
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
12
11
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
104
49
32
26
15
12
11
10
9
7
3
1
Optionen
Immunogen A synthesized peptide derived from human NR1I2
Isotyp IgG
Spezifität NR1I2 Antibody detects endogenous levels of total NR1I2
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Antigen
Andere Bezeichnung NR1I2 (NR1I2 Antibody Abstract)
Hintergrund

Description: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.

Gene: NR1I2

Molekulargewicht 50kDa
Gen-ID 8856
UniProt O75469
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Applikations-hinweise WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder des Herstellers
Image no. 1 for anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) antibody (ABIN6263716) Western blot analysis of extracts from B16F10, using NR1I2 Antibody. The lane on the ...
Image no. 2 for anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) antibody (ABIN6263716) Western blot analysis of extracts of Mouse liver,using NR1I2 antibody. The lane on th...
Image no. 3 for anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) antibody (ABIN6263716) ABIN6276741 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyd...
Image no. 4 for anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) antibody (ABIN6263716) ABIN6276741 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permea...
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