MFN1 Antikörper (Internal Region)
Kurzübersicht für MFN1 Antikörper (Internal Region) (ABIN6263261)
Target
Alle MFN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Internal Region
-
Spezifität
- Mitofusin Antibody detects endogenous levels of total Mitofusin.
-
Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human Mitofusin, corresponding to a region within the internal amino acids.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- MFN1 (Mitofusin 1 (MFN1))
-
Andere Bezeichnung
- MFN1
-
Hintergrund
-
Description: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12475957, PubMed:12759376, PubMed:27920125, PubMed:28114303). Membrane clustering requires GTPase activity (PubMed:27920125). It may involve a major rearrangement of the coiled coil domains (PubMed:27920125, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12475957, PubMed:12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:12759376). Has low GTPase activity (PubMed:27920125, PubMed:28114303).
Gene: MFN1
-
Molekulargewicht
- 84 kDa
-
Gen-ID
- 55669
-
UniProt
- Q8IWA4
Target
-