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MFN1 Antikörper (AA 1-741)

MFN1 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 3C9 unconjugated
Produktnummer ABIN527615
  • Target Alle MFN1 Antikörper anzeigen
    MFN1 (Mitofusin 1 (MFN1))
    Bindungsspezifität
    • 16
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-741
    Reaktivität
    • 50
    • 31
    • 27
    • 21
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 4
    • 3
    • 1
    Maus
    Klonalität
    • 59
    • 11
    Monoklonal
    Konjugat
    • 33
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MFN1 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 25
    • 15
    • 12
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, RNA Interference (RNAi)
    Verwendungszweck
    Mouse monoclonal antibody raised against a full length recombinant MFN1.
    Sequenz
    MAEPVSPLKH FVLAKKAITA IFDQLLEFVT EGSHFVEATY KNPELDRIAT EDDLVEMQGY KDKLSIIGEV LSRRHMKVAF FGRTSSGKSS VINAMLWDKV LPSGIGHITN CFLSVEGTDG DKAYLMTEGS DEKKSVKTVN QLAHALHMDK DLKAGCLVRV FWPKAKCALL RDDLVLVDSP GTDVTTELDS WIDKFCLDAD VFVLVANSES TLMNTEKHFF HKVNERLSKP NIFILNNRWD ASASEPEYME DVRRQHMERC LHFLVEELKV VNALEAQNRI FFVSAKEVLS ARKQKAQGMP ESGVALAEGF HARLQEFQNF EQIFEECISQ SAVKTKFEQH TIRAKQILAT VKNIMDSVNL AAEDKRHYSV EEREDQIDRL DFIRNQMNLL TLDVKKKIKE VTEEVANKVS CAMTDEICRL SVLVDEFCSE FHPNPDVLKI YKSELNKHIE DGMGRNLADR CTDEVNALVL QTQQEIIENL KPLLPAGIQD KLHTLIPCKK FDLSYNLNYH KLCSDFQEDI VFRFSLGWSS LVHRFLGPRN AQRVLLGLSE PIFQLPRSLA STPTAPTTPA TPDNASQEEL MITLVTGLAS VTSRTSMGII IVGGVIWKTI GWKLLSVSLT MYGALYLYER LSWTTHAKER AFKQQFVNYA TEKLRMIVSS TSANCSHQVK QQIATTFARL CQQVDITQKQ LEEEIARLPK EIDQLEKIQN NSKLLRNKAV QLENELENFT KQFLPSSNEE S
    Spezifität
    This antibody may cross react with MFN2 protein.
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    MFN1 (AAH40557, 1 a.a. ~ 741 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    3C9
    Isotyp
    IgG2a
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).

    Baba, Kashiwagi, Arimitsu, Kogure, Edo, Maruyama, Nakao, Nakanishi, Kinoshita, Frohman, Yamamoto, Tani: "Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11497-511, (2014) (PubMed).

    Yue, Chen, Liu, Yan, Chen, Feng, Yan, Wu, Du, Wang, Liu, Huang, Xia, Liu, Wang, Jin, Wang, Song, Hao, Chen: "A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30." in: Cell research, Vol. 24, Issue 4, pp. 482-96, (2014) (PubMed).

    Shiba-Fukushima, Inoshita, Hattori, Imai: "Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy." in: The Journal of biological chemistry, Vol. 289, Issue 48, pp. 33131-6, (2014) (PubMed).

    Takamura, Koyama, Matsuzaki, Yamada, Hattori, Miyata, Takemoto, Tohyama, Katayama: "TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression." in: PLoS ONE, Vol. 7, Issue 12, pp. e51912, (2013) (PubMed).

    Goller, Seibold, Kremmer, Voos, Kolanus: "Atad3 function is essential for early post-implantation development in the mouse." in: PLoS ONE, Vol. 8, Issue 1, pp. e54799, (2013) (PubMed).

    Russell, Lamon, Boon, Wada, Güller, Brown, Chibalin, Zierath, Snow, Stepto, Wadley, Akimoto: "Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training." in: The Journal of physiology, Vol. 591, Issue Pt 18, pp. 4637-53, (2013) (PubMed).

    Ban-Ishihara, Ishihara, Sasaki, Mihara, Ishihara: "Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 29, pp. 11863-8, (2013) (PubMed).

    Fülöp, Rajki, Katona, Szanda, Spät: "Extramitochondrial OPA1 and adrenocortical function." in: Molecular and cellular endocrinology, Vol. 381, Issue 1-2, pp. 70-9, (2013) (PubMed).

    Lin, Lai, Lin, Lin, Wang, Lin, Lee, Wang, Chen: "Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation." in: Cell death and differentiation, Vol. 20, Issue 1, pp. 139-53, (2012) (PubMed).

    Shiba-Fukushima, Imai, Yoshida, Ishihama, Kanao, Sato, Hattori: "PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy." in: Scientific reports, Vol. 2, pp. 1002, (2012) (PubMed).

    Bui, Gilady, Fitzsimmons, Benson, Lynes, Gesson, Alto, Strack, Scott, Simmen: "Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31590-602, (2010) (PubMed).

    Zanna, Ghelli, Porcelli, Karbowski, Youle, Schimpf, Wissinger, Pinti, Cossarizza, Vidoni, Valentino, Rugolo, Carelli: "OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion." in: Brain : a journal of neurology, Vol. 131, Issue Pt 2, pp. 352-67, (2008) (PubMed).

    Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).

  • Target
    MFN1 (Mitofusin 1 (MFN1))
    Andere Bezeichnung
    MFN1 (MFN1 Produkte)
    Synonyme
    mfn1 antikoerper, zgc:66150 antikoerper, mitofusin-1 antikoerper, MFN1 antikoerper, MFN2 antikoerper, hfzo1 antikoerper, hfzo2 antikoerper, 2310002F04Rik antikoerper, 6330416C07Rik antikoerper, D3Ertd265e antikoerper, HR2 antikoerper, mKIAA4032 antikoerper, Fzo1b antikoerper, mitofusin 1b antikoerper, mitofusin 1 antikoerper, mitofusin 1 S homeolog antikoerper, mfn1b antikoerper, MFN1 antikoerper, mfn1.S antikoerper, mfn1 antikoerper, Mfn1 antikoerper
    Hintergrund
    Full Gene Name: mitofusin 1
    Synonyms: DKFZp762F247,FLJ20693,MGC41806,hfzo1,hfzo2
    Gen-ID
    55669
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