HORMAD1 Antikörper (C-Term)

Produktnummer ABIN6262338

Der Kaninchen Polyklonal Anti-HORMAD1-Antikörper wurde für ELISA, WB, ICC und IF validiert. Er ist geeignet, HORMAD1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für HORMAD1 Antikörper (C-Term) (ABIN6262338)

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HORMAD1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-HORMAD1 Antikörper

Bindungsspezifität: C-Term

Spezifität: HORMAD1 Antibody detects endogenous levels of total HORMAD1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HORMAD1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HORMAD1

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Andere Bezeichnung: HORMAD1

Hintergrund:

Description: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

Gene: HORMAD1

Molekulargewicht: 45kDa

Gen-ID: 84072

UniProt: Q86X24

Pathways: M Phase