HLA-DMA Antikörper
Kurzübersicht für HLA-DMA Antikörper (ABIN6262285)
Target
Alle HLA-DMA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- HLA-DMA Antibody detects endogenous levels of total HLA-DMA
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Kreuzreaktivität
- Human, Ratte (Rattus)
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human HLA-DMA
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-3000 IHC 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
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Andere Bezeichnung
- HLA-DMA
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Hintergrund
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Description: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Gene: HLA-DMA
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Molekulargewicht
- 29 kDa
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UniProt
- P28067
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Pathways
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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