HDAC4 Antikörper (Internal Region)
Kurzübersicht für HDAC4 Antikörper (Internal Region) (ABIN6262180)
Target
Alle HDAC4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- HDAC4 Antibody detects endogenous levels of total HDAC4.
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Homologie
- Pig,Zebrafish,Bovine,Sheep,Dog,Chicken,Xenopus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human HDAC4, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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anti-Histone Deacetylase 4 (HDAC4) (AA 904-1076) antibody
HDAC4 Reaktivität: Maus WB, IHC, IP, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 551-648) antibodyHDAC4 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 2B11 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 456-592) antibodyHDAC4 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 7E2E6 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 456-592) antibodyHDAC4 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 5E4A5 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 451-650) antibodyHDAC4 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077) antibodyHDAC4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 530-630) antibodyHDAC4 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) antibodyHDAC4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (pSer220), (pSer246), (pSer259) antibodyHDAC4 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077), (C-Term) antibodyHDAC4 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33667 unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Andere Bezeichnung
- HDAC4
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Hintergrund
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Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).
Gene: HDAC4
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Molekulargewicht
- 119kDa
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Gen-ID
- 9759
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UniProt
- P56524
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Target
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