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HDAC3 Antikörper (C-Term)

Name: HDAC3 Antikörper (C-Term)
SKU: ABIN6262179
Price: 864 EUR
Availability: InStock

HDAC3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of various sample,using GATA3 antibody. (HDAC3 Antikörper (C-Term))

ABIN6269054 at 1/100 staining Human gastric tissue by IHC-P. (HDAC3 Antikörper (C-Term))

IHC

ABIN6269054 staining MCF-7 cells by ICC/IF. (HDAC3 Antikörper (C-Term))

IF/ICC

Western blot analysis of HDAC3 expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (HDAC3 Antikörper (C-Term))

Western blot analysis of HDAC3 expression in Mouse kidney lysate (HDAC3 Antikörper (C-Term))

Western blot analysis of extracts from various samples, using HDAC3 Antibody. (HDAC3 Antikörper (C-Term))

6 Abbildungen

Produktnummer ABIN6262179

Datenblatt (PDF)

Target Alle HDAC3 Antikörper anzeigen

HDAC3 (Histone Deacetylase 3 (HDAC3))
Bindungsspezifität
16

15

14

11

8

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
117

71

68

7

5

5

4

4

3

3

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
91

25

1
Kaninchen
Passende Sekundärantikörper
Klonalität
89

28
Polyklonal
Konjugat
63

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1
Dieser HDAC3 Antikörper ist unkonjugiert
Applikation
90

47

35

26

25

24

16

16

14

9

6

5

4

2

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität

HDAC3 Antibody detects endogenous levels of total HDAC3.

Homologie

Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human HDAC3, corresponding to a region within C-terminal amino acids.

Isotyp

IgG
anti-Histone Deacetylase 3 (HDAC3) (pSer424) antibody
HDAC3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibody
HDAC3 Reaktivität: Human WB, ELISA, IHC, IF, ChIP Wirt: Kaninchen Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 319-428) antibody
HDAC3 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2A3 unconjugated

anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibody
HDAC3 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) antibody
HDAC3 Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibody
HDAC3 Reaktivität: Human ELISA, IF, IP Wirt: Maus Monoclonal 2F9-4B7 unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 31-130) antibody
HDAC3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) antibody
HDAC3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Monoclonal 4D4 unconjugated Recombinant Antibody

anti-Histone Deacetylase 3 (HDAC3) (AA 224-428) antibody
HDAC3 Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 3A7B5 unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 224-428) antibody
HDAC3 Reaktivität: Human WB, ELISA, ICC Wirt: Maus Monoclonal 7G6C5 unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Target

HDAC3 (Histone Deacetylase 3 (HDAC3))

Andere Bezeichnung

HDAC3 (HDAC3 Produkte)

Hintergrund

Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1, increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation (PubMed:21444723, PubMed:23911289). Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI3K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell (EC) survival under disturbed flow/oxidative stress (PubMed:25190803).
Gene: HDAC3

Molekulargewicht

48kDa

Gen-ID

8841

UniProt

O15379

Pathways

Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development