GPSM2 Antikörper (C-Term)

Produktnummer ABIN6262065

Der Kaninchen Polyklonal Anti-GPSM2-Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, GPSM2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GPSM2 Antikörper (C-Term) (ABIN6262065)

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPSM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-GPSM2 Antikörper

Bindungsspezifität: C-Term

Spezifität: GPSM2 Antibody detects endogenous levels of total GPSM2.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPSM2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GPSM2

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Andere Bezeichnung: GPSM2

Hintergrund:

Description: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed:22327364). Plays a role in metaphase spindle orientation (PubMed:22327364). Plays also an important role in asymmetric cell divisions (PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity).

Gene: GPSM2

Molekulargewicht: 77 kDa

Gen-ID: 29899

UniProt: P81274

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling