DAPK2 Antikörper (C-Term)

Produktnummer ABIN6261222

Der Kaninchen Polyklonal Anti-DAPK2-Antikörper wurde für WB, ELISA, IHC, IF und ICC validiert. Er ist geeignet, DAPK2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für DAPK2 Antikörper (C-Term) (ABIN6261222)

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAPK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-DAPK2 Antikörper

Bindungsspezifität: C-Term

Spezifität: DAPK2 Antibody detects endogenous levels of total DAPK2.

Homologie: Pig,Horse,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DAPK2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DAPK2

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Andere Bezeichnung: DAPK2

Hintergrund:

Description: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).

Gene: DAPK2

Molekulargewicht: 42 kDa

Gen-ID: 23604

UniProt: Q9UIK4