CRTC3 Antikörper (Internal Region)

Produktnummer ABIN6261047

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CRTC3 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CRTC3 Antikörper (Internal Region) (ABIN6261047)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRTC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CRTC3 Antikörper

Bindungsspezifität: Internal Region

Spezifität: CRTC3 Antibody detects endogenous levels of total CRTC3.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CRTC3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Andere Bezeichnung: CRTC3

Hintergrund:

Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Gene: CRTC3

Molekulargewicht: 76 kDa

Gen-ID: 64784

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion