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CaMK2 alpha/delta Antikörper

Reaktivität: Human, Maus, Ratte IF, IHC, WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260427
  • Target Alle CaMK2 alpha/delta Produkte
    CaMK2 alpha/delta
    Reaktivität
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 3
    Kaninchen
    Klonalität
    • 3
    Polyklonal
    Konjugat
    • 3
    Dieser CaMK2 alpha/delta Antikörper ist unkonjugiert
    Applikation
    Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Spezifität
    CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CaMK2 alpha/delta
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Cao, Xiao, Wang, Weng, Ding, Zhu, Lu: "Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).

  • Target
    CaMK2 alpha/delta
    Abstract
    CaMK2 alpha/delta Produkte
    Hintergrund

    Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

    Gene: CAMK2A

    Molekulargewicht
    50kDa
    Gen-ID
    815
    UniProt
    Q9UQM7, Q13557
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