CaMKIIalpha/delta Antikörper (pThr286)
Kurzübersicht für CaMKIIalpha/delta Antikörper (pThr286) (ABIN6256533)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pThr286
-
Verwendungszweck
- Phospho-CaMKII alpha/delta (Thr286) Antibody
-
Spezifität
- Phospho-CaMK2 (Thr286) Antibody detects endogenous levels of CaMK2 only when phosphorylated at Threonine 286
-
Homologie
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
-
Immunogen
- A synthesized peptide derived from human CaMK2 alpha/delta around the phosphorylation site of Thr286.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- CaMKIIalpha/delta
-
Andere Bezeichnung
- CaMKII alpha/delta
-
Hintergrund
-
Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Gene: CAMK2A
-
Molekulargewicht
- 50kDa
-
Gen-ID
- 815
-
UniProt
- Q9UQM7
Target
-