BRAP Antikörper (C-Term)

Produktnummer ABIN6260302

Dieses Anti-BRAP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRAP in WB, ELISA, IF und ICC. Geeignet für Human.

Kurzübersicht für BRAP Antikörper (C-Term) (ABIN6260302)

Target: BRAP (BRCA1 Associated Protein (BRAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-BRAP Antikörper

Bindungsspezifität: C-Term

Spezifität: BRAP Antibody detects endogenous levels of total BRAP.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BRAP, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu BRAP

Target: BRAP (BRCA1 Associated Protein (BRAP))

Andere Bezeichnung: BRAP

Hintergrund:

Description: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Gene: BRAP

Molekulargewicht: 67 kDa

Gen-ID: 8315

UniProt: Q7Z569