BMPR1A Antikörper (N-Term)
Kurzübersicht für BMPR1A Antikörper (N-Term) (ABIN6260291)
Target
Alle BMPR1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- BMPR1A Antibody detects endogenous levels of total BMPR1A.
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Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human BMPR1A, corresponding to a region within N-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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Andere Bezeichnung
- BMPR1A
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Hintergrund
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Description: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Gene: BMPR1A
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Molekulargewicht
- 60kDa
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Gen-ID
- 657
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UniProt
- P36894
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Pathways
- Stem Cell Maintenance
Target
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