APOC1 Antikörper (Internal Region)

Produktnummer ABIN6259989

Der Kaninchen Polyklonal Anti-APOC1-Antikörper wurde für WB, ICC, ELISA und IF validiert. Er ist geeignet, APOC1 in Proben von Human zu detektieren.

Kurzübersicht für APOC1 Antikörper (Internal Region) (ABIN6259989)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Produktdetails anti-APOC1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: APOC1 Antibody detects endogenous levels of total APOC1.

Homologie: Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APOC1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Andere Bezeichnung: APOC1

Hintergrund:

Description: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10 % of the protein of the VLDL and 2 % of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.

Gene: APOC1

Molekulargewicht: 9 kDa

Gen-ID: 341

UniProt: P02654

Pathways: Apoptose