APLF Antikörper (Internal Region)

Produktnummer ABIN6259979

Produktdetails anti-APLF Antikörper

Target: APLF (Aprataxin and PNKP Like Factor (APLF))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLF Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: APLF Antibody detects endogenous levels of total APLF.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APLF, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu APLF

Target: APLF (Aprataxin and PNKP Like Factor (APLF))

Andere Bezeichnung: APLF (APLF Produkte)

Synonyme: apfl antikoerper, palf antikoerper, xip1 antikoerper, APLF antikoerper, C2orf13 antikoerper, DKFZp459J1223 antikoerper, APFL antikoerper, PALF antikoerper, Xip1 antikoerper, 2010301N04Rik antikoerper, AI452191 antikoerper, RGD1565557 antikoerper, aprataxin and PNKP like factor antikoerper, APLF antikoerper, aplf antikoerper, Aplf antikoerper

Hintergrund:

Description: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.

Gene: APLF

Molekulargewicht: 57kDa

Gen-ID: 200558

UniProt: Q8IW19

Pathways: DNA Reparatur