Iba1 Antikörper (C-Term)

Produktnummer ABIN6259839

Produktdetails anti-Iba1 Antikörper

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Iba1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: AIF1/IBA1 Antibody detects endogenous levels of total AIF1/IBA1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AIF1/IBA1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Andere Bezeichnung: AIF1 (IBA1 Produkte)

Synonyme: AIF-1 antikoerper, IBA1 antikoerper, IRT-1 antikoerper, IRT1 antikoerper, AI607846 antikoerper, D17H6S50E antikoerper, G1 antikoerper, Iba1 antikoerper, Bart1 antikoerper, iba1 antikoerper, mrf-1 antikoerper, fa04b11 antikoerper, wu:fa04b11 antikoerper, AIF antikoerper, AIF1 antikoerper, aif1 antikoerper, allograft inflammatory factor 1 antikoerper, AIF1 antikoerper, Aif1 antikoerper, aif1 antikoerper

Hintergrund:

Description: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Gene: AIF1

Molekulargewicht: 17kDa

Gen-ID: 199

UniProt: P55008

Pathways: Smooth Muscle Cell Migration