Adiponectin Receptor 1 Antikörper (C-Term)

Produktnummer ABIN6259800

Der Kaninchen Polyklonal Anti-Adiponectin Receptor 1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, Adiponectin Receptor 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Adiponectin Receptor 1 Antikörper (C-Term) (ABIN6259800)

Target: Adiponectin Receptor 1 (ADIPOR1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adiponectin Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Adiponectin Receptor 1 Antikörper

Bindungsspezifität: C-Term

Spezifität: ADIPOR1 Antibody detects endogenous levels of total ADIPOR1.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ADIPOR1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Andere Bezeichnung: ADIPOR1

Hintergrund:

Description: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).

Gene: ADIPOR1

Molekulargewicht: 43kDa

Gen-ID: 51094

UniProt: Q96A54

Pathways: AMPK Signaling