WEE2 Antikörper (Internal Region)

Produktnummer ABIN6259536

Der Kaninchen Polyklonal anti-WEE2 Antikörper wird verwendet zum Nachweis von WEE2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ICC und IF.

Kurzübersicht für WEE2 Antikörper (Internal Region) (ABIN6259536)

Target: WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WEE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-WEE2 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: WEE2 Antibody

Spezifität: WEE2 Antibody detects endogenous levels of total WEE2

Homologie: Pig,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WEE2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu WEE2

Target: WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))

Andere Bezeichnung: WEE2

Hintergrund:

Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

Gene: WEE2

Molekulargewicht: 60 kDa

Gen-ID: 494551

UniProt: P0C1S8

Pathways: M Phase