PSPC1 Antikörper (C-Term)

Produktnummer ABIN6259284

Der Kaninchen Polyklonal Anti-PSPC1-Antikörper wurde für WB, ELISA, IHC, ICC und IF validiert. Er ist geeignet, PSPC1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PSPC1 Antikörper (C-Term) (ABIN6259284)

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-PSPC1 Antikörper

Bindungsspezifität: C-Term

Spezifität: PSPC1 Antibody detects endogenous levels of total PSPC1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSPC1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Andere Bezeichnung: PSPC1

Hintergrund:

Description: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of nuclear paraspeckles. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.

Gene: PSPC1

Molekulargewicht: 58 kDa

Gen-ID: 55269

UniProt: Q8WXF1