NK2 Homeobox 5 Antikörper (Internal Region)
Kurzübersicht für NK2 Homeobox 5 Antikörper (Internal Region) (ABIN6259127)
Target
Alle NK2 Homeobox 5 (NKX2-5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- Nkx2.5 Antibody detects endogenous levels of total Nkx2.5.
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Homologie
- Pig,Bovine,Horse,Sheep,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Nkx2.5, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Haltbarkeit
- 12 months
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- NK2 Homeobox 5 (NKX2-5)
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Andere Bezeichnung
- NKX2-5
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Hintergrund
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Description: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.
Gene: NKX2-5
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Molekulargewicht
- 50 kDa
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Gen-ID
- 1482
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UniProt
- P52952
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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