MCF2L Antikörper (Internal Region)
Kurzübersicht für MCF2L Antikörper (Internal Region) (ABIN6258277)
Target
Alle MCF2L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- MCF2L Antibody detects endogenous levels of total MCF2L.
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human MCF2L, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Haltbarkeit
- 12 months
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- MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))
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Andere Bezeichnung
- MCF2L
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Hintergrund
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Description: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 (PubMed:15157669).
Gene: MCF2L
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Gen-ID
- 23263
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UniProt
- O15068
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Pathways
- Neurotrophin Signalübertragung, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis
Target
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