MCF2L Antikörper

Produktnummer ABIN7229596

Der Kaninchen Polyklonal anti-MCF2L Antikörper (ABIN7229596) detektiert spezifisch MCF2L in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für MCF2L Antikörper (ABIN7229596)

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCF2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MCF2L Antikörper

Verwendungszweck: Rabbit Anti-MCF2L Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MCF2L protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MCF2L protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MCF2L

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Andere Bezeichnung: MCF2L

Hintergrund: Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like proteinMCF2L encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. MCF2L (MCF. Cell Line Derived Transforming Sequence Like) is a Protein Coding gene. Diseases associated with MCF2L include Atypical Autism and Osteoarthritis. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway.

Molekulargewicht: 125kD

Gen-ID: 23263

UniProt: O15068

Pathways: Neurotrophin Signalübertragung, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis