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KCNK4 Antikörper (C-Term)

Dieses Anti-KCNK4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KCNK4 in WB, ELISA, IHC, IF und ICC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN6257437

Kurzübersicht für KCNK4 Antikörper (C-Term) (ABIN6257437)

Target

Alle KCNK4 Antikörper anzeigen
KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Reaktivität

  • 22
  • 11
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 21
  • 1
Kaninchen

Klonalität

  • 20
  • 1
  • 1
Polyklonal

Konjugat

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser KCNK4 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    KCNK4 Antibody detects endogenous levels of total KCNK4.

    Homologie

    Pig,Bovine,Horse,Rabbit,Dog

    Aufreinigung

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human KCNK4, corresponding to a region within C-terminal amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C. Stable for 12 months from date of receipt.

    Haltbarkeit

    12 months
  • Target

    KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

    Andere Bezeichnung

    KCNK4

    Hintergrund

    Description: Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular  pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro), raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity).

    Gene: KCNK4

    Molekulargewicht

    45 kDa

    Gen-ID

    50801

    UniProt

    Q9NYG8
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