IL-11 Antikörper (N-Term)
Kurzübersicht für IL-11 Antikörper (N-Term) (ABIN6257286)
Target
Alle IL-11 (IL11) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- IL11 Antibody detects endogenous levels of total IL11.
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Homologie
- Pig,Bovine,Horse,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Haltbarkeit
- 12 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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Andere Bezeichnung
- IL11
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Hintergrund
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Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Gene: IL11
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Molekulargewicht
- 27 kDa
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Gen-ID
- 3589
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UniProt
- P20809
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Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
Target
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