BMP10 Antikörper (Internal Region)
Kurzübersicht für BMP10 Antikörper (Internal Region) (ABIN6256960)
Target
Alle BMP10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- BMP10 Antibody detects endogenous levels of total BMP10.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human BMP10, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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anti-Bone Morphogenetic Protein 10 (BMP10) (AA 315-424) antibody
BMP10 Reaktivität: Human WB, IHC Wirt: Maus Monoclonal A1 unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (AA 7-35), (N-Term) antibodyBMP10 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1867-1868 unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (C-Term) antibodyBMP10 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (AA 314-421) antibodyBMP10 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (AA 22-316) antibodyBMP10 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (AA 1-424) antibodyBMP10 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (AA 91-140) antibodyBMP10 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Fledermaus, Affe, Schwein, Zebrafisch (Danio rerio), Huhn WB Wirt: Kaninchen Polyclonal unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (N-Term) antibodyBMP10 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Bone Morphogenetic Protein 10 (BMP10) (N-Term) antibodyBMP10 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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Andere Bezeichnung
- BMP10
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Hintergrund
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Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Gene: BMP10
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Molekulargewicht
- 48 kDa
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Gen-ID
- 27302
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UniProt
- O95393
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Pathways
- Hormone Activity, Regulation of Muscle Cell Differentiation
Target
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