AFT1 Antikörper (Internal Region)
Kurzübersicht für AFT1 Antikörper (Internal Region) (ABIN6256913)
Target
Alle AFT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Internal Region
-
Spezifität
- ATF1 Antibody detects endogenous levels of total ATF1.
-
Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human ATF1, corresponding to a region within the internal amino acids.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- AFT1 (Activating Transcription Factor 1 (AFT1))
-
Andere Bezeichnung
- ATF1
-
Hintergrund
-
Description: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Gene: ATF1
-
Molekulargewicht
- 36 kDa
-
Gen-ID
- 466
-
UniProt
- P18846
-
Pathways
- Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
Target
-