Serotonin Receptor 6 Antikörper (Internal Region)

Produktnummer ABIN6256884

Der Kaninchen Polyklonal anti-Serotonin Receptor 6 Antikörper wird verwendet zum Nachweis von Serotonin Receptor 6 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ICC und IF.

Kurzübersicht für Serotonin Receptor 6 Antikörper (Internal Region) (ABIN6256884)

Target: Serotonin Receptor 6 (HTR6)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-Serotonin Receptor 6 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: 5HT6 Receptor Antibody

Spezifität: 5HT6 Receptor Antibody detects endogenous levels of total 5HT6 Receptor.

Homologie: Pig,Bovine,Horse,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human 5HT6 Receptor, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Serotonin Receptor 6

Target: Serotonin Receptor 6 (HTR6)

Andere Bezeichnung: 5HT6 Receptor

Hintergrund:

Description: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).

Gene: HTR6

Molekulargewicht: 47 kDa

Gen-ID: 3362

UniProt: P50406

Pathways: JAK-STAT Signalweg