Histone H2A Antikörper (H2AT121ph)
Kurzübersicht für Histone H2A Antikörper (H2AT121ph) (ABIN6256470)
Target
Alle Histone H2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- H2AT121ph
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Verwendungszweck
- Phospho-Histone H2A (Thr121) Antibody
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Spezifität
- Phospho-Histone H2A (Thr121) Antibody detects endogenous levels of Histone H2A only when phosphorylated at Threonine 121
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Homologie
- Bovine,Xenopus
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Histone H2A around the phosphorylation site of Thr121.
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:50-1:200, WB 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Histone H2A
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Hintergrund
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM
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Molekulargewicht
- 15kDa
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Gen-ID
- 83, 298, 330
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UniProt
- P0C0S8
Target
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