Synaptotagmin Antikörper (pSer309)

Produktnummer ABIN6256263

Der Kaninchen Polyklonal Anti-Synaptotagmin-Antikörper wurde für WB, IHC, ELISA, IF und ICC validiert. Er ist geeignet, Synaptotagmin in Proben von Ratte, Maus und Human zu detektieren.

Kurzübersicht für Synaptotagmin Antikörper (pSer309) (ABIN6256263)

Target: Synaptotagmin (SYT)

Reaktivität: Ratte, Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptotagmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Synaptotagmin Antikörper

Bindungsspezifität: pSer309

Spezifität: Phospho-Synaptotagmin (Ser309) Antibody detects endogenous levels of Synaptotagmin only when phosphorylated at Serine 309

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Serine 309

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Synaptotagmin

Target: Synaptotagmin (SYT)

Andere Bezeichnung: Synaptotagmin

Hintergrund:

Description: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Gene: SYT1

Molekulargewicht: 47kDa

Gen-ID: 6857

UniProt: P21579, Q8N9I0