SYT1/2 Antikörper (pThr202)

Produktnummer ABIN6256502

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SYT1/2 in WB, IHC, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SYT1/2 Antikörper (pThr202) (ABIN6256502)

Target: SYT1/2 (Synaptotagmin 1/2 (SYT1/2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYT1/2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-SYT1/2 Antikörper

Bindungsspezifität: pThr202

Verwendungszweck: Phospho-Synaptotagmin 1/2 (Thr202) Antibody

Spezifität: Phospho-Synaptotagmin (Thr202) Antibody detects endogenous levels of Synaptotagmin only when phosphorylated at Threonine 202

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Synaptotagmin 1/2 around the phosphorylation site of Thr202.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SYT1/2

Target: SYT1/2 (Synaptotagmin 1/2 (SYT1/2))

Andere Bezeichnung: Synaptotagmin 1/2

Hintergrund:

Description: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Gene: SYT1

Molekulargewicht: 60kDa

Gen-ID: 6857

UniProt: P21579