SMAD1 Antikörper (pSer187)
Kurzübersicht für SMAD1 Antikörper (pSer187) (ABIN6256175)
Target
Alle SMAD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer187
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Spezifität
- Phospho-Smad1 (Ser187) Antibody detects endogenous levels of Smad1 only when phosphorylated at Serine 187.
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Homologie
- Bovine,Sheep,Rabbit,Chicken,Xenopus
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Smad1 around the phosphorylation site of Ser187.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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: "Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 2, pp. 386-397, (2017) (PubMed).
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: "Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 2, pp. 386-397, (2017) (PubMed).
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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Andere Bezeichnung
- SMAD1
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Hintergrund
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Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Gene: SMAD1
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Molekulargewicht
- 60/55kDa
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Gen-ID
- 4086
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UniProt
- Q15797
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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