BCL2L1 Antikörper (pSer62)
Kurzübersicht für BCL2L1 Antikörper (pSer62) (ABIN6255430)
Target
Alle BCL2L1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pSer62
-
Spezifität
- Phospho-BCL-XL (Ser62) Antibody detects endogenous levels of BCL-XL only when phosphorylated at Serine 62.
-
Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
-
Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
Immunogen
- A synthesized peptide derived from human BCL-XL around the phosphorylation site of Ser62.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- BCL2L1 (BCL2-Like 1 (BCL2L1))
-
Andere Bezeichnung
- BCL2L1
-
Hintergrund
-
Description: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Gene: BCL2L1
-
Molekulargewicht
- 30kDa
-
Gen-ID
- 598
-
UniProt
- Q07817
-
Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
Target
-