EIF4B Antikörper (pSer422)
Kurzübersicht für EIF4B Antikörper (pSer422) (ABIN6255321)
Target
Alle EIF4B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer422
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Spezifität
- Phospho-eIF4B (Ser422) Antibody detects endogenous levels of eIF4B only when phosphorylated at Ser422.
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Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
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Andere Bezeichnung
- EIF4B
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Hintergrund
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Description: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Gene: EIF4B
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Molekulargewicht
- 69 kDa
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Gen-ID
- 1975
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UniProt
- P23588
Target
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