HDAC8 Antikörper (pSer39)
Kurzübersicht für HDAC8 Antikörper (pSer39) (ABIN6255291)
Target
Alle HDAC8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer39
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Spezifität
- Phospho-HDAC8 (Ser39) Antibody detects endogenous levels of HDAC8 only when phosphorylated at Serine 39.
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Homologie
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- HDAC8 (Histone Deacetylase 8 (HDAC8))
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Andere Bezeichnung
- HDAC8
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Hintergrund
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Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
Gene: HDAC8
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Molekulargewicht
- 42kDa
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Gen-ID
- 55869
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UniProt
- Q9BY41
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Pathways
- Cellular Glucan Metabolic Process
Target
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