EEF2K Antikörper (pSer366)
Kurzübersicht für EEF2K Antikörper (pSer366) (ABIN6255261)
Target
Alle EEF2K Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer366
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Spezifität
- Phospho-eEF2k (Ser366) Antibody detects endogenous levels of eEF2k.
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human eEF2k around the phosphorylation site of Ser366.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
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Andere Bezeichnung
- eEF2k
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Hintergrund
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Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Gene: EEF2K
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Molekulargewicht
- 105kDa
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Gen-ID
- 29904
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UniProt
- O00418
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Pathways
- AMPK Signaling
Target
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