EEF2K Antikörper (N-Term)

Produktnummer ABIN2856812

Produktdetails anti-EEF2K Antikörper

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF2K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to EEF2K (eukaryotic elongation factor-2 kinase)
eEF-2K antibody [N1N3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human eEF2K. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse liver , A431 , H1299 , HeLa , HepG2 , PC-12

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu EEF2K

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Andere Bezeichnung: eukaryotic elongation factor 2 kinase (EEF2K Produkte)

Synonyme: HSU93850 antikoerper, eEF-2K antikoerper, C86191 antikoerper, SMEF2K antikoerper, eEF-2 kinase antikoerper, cb365 antikoerper, fa04b08 antikoerper, wu:fa04b08 antikoerper, zgc:100973 antikoerper, eukaryotic elongation factor 2 kinase antikoerper, eukaryotic elongation factor-2 kinase antikoerper, EEF2K antikoerper, Eef2k antikoerper, eef2k antikoerper, LOC101930123 antikoerper

Hintergrund: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Molekulargewicht: 82 kDa

Gen-ID: 29904

UniProt: O00418

Pathways: AMPK Signaling