ErbB2/Her2 Antikörper (C-Term)

Produktnummer ABIN6254225

Der Ziege Polyklonal anti-ErbB2/Her2 Antikörper wird verwendet zum Nachweis von ErbB2/Her2 in Proben von Human, Maus, Ratte, Hund, Affe, Pferd, Schwein, Kaninchen, Rind (Kuh), Hamster, Avian, Cat, Huhn, Esel, Ziege, Meerschweinchen und Schaf. Er wurde validiert für WB, IHC (p) und IHC (fro).

Kurzübersicht für ErbB2/Her2 Antikörper (C-Term) (ABIN6254225)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reaktivität: Human, Maus, Ratte, Hund, Affe, Pferd, Schwein, Kaninchen, Rind (Kuh), Hamster, Avian, Cat, Huhn, Esel, Ziege, Meerschweinchen, Schaf

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ErbB2/Her2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ErbB2/Her2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-ERBB2

Sequenz: MPHPPPAFSP AFDNLYYWDQ DPPERGAPPS TFKGTPTAEN PEYLGLDVPV

Spezifität: Detects endogenous levels of ERBB2 by Western blot.

Produktmerkmale: Erb-b2 receptor tyrosine kinase

Aufreinigung: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 1,177 aa to the C-terminus of human ERBB2 produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Details zu ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Andere Bezeichnung: ERBB2

Hintergrund:

Goat polyclonal antibody to ERBB2. This protein is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases containing a single transmembrane domain and has an approximate molecular weight of 185 kDa. ERBB2 contains no ligand binding domain and interacts with other EGF receptor family members to form a heterodimer, stabilize ligand binding, and enhance kinase-mediated downstream signalling. It has been shown to be involved in embryonic development and cancer progression.

CD340, erb-b2 receptor tyrosine kinase 2, HER2, HER-2, HER-2/neu, MLN 19, NEU, NGL and TKR1 antibody.

Molekulargewicht: 185 kDa

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development