Cathepsin D Antikörper (C-Term)

Produktnummer ABIN6254162

Es gibt 1 Publikation für dieses Produkt. Der Ziege Polyklonal anti-Cathepsin D Antikörper wird verwendet zum Nachweis von Cathepsin D in Proben von Human, Maus, Ratte, Affe, Hamster, Rind (Kuh), Schwein, Kaninchen, Hund, Pferd, Meerschweinchen, Avian, Cat, Huhn, Esel, Ziege und Schaf. Er wurde validiert für WB, IF, IHC (p), IHC (fro) und IEM.

Kurzübersicht für Cathepsin D Antikörper (C-Term) (ABIN6254162)

Target: Cathepsin D (CTSD)

Reaktivität: Human, Maus, Ratte, Affe, Hamster, Rind (Kuh), Schwein, Kaninchen, Hund, Pferd, Meerschweinchen, Avian, Cat, Huhn, Esel, Ziege, Schaf

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

Produktdetails anti-Cathepsin D Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Cathepsin D

Sequenz: DQVEVASGLT LCKEGCEAIV DTGTSLMVGP VDEVRELQKA IGAVPLIQGE YMIPCEKVST LPAITLKLGG KGYKLSPEDY TLKVSQAGKT LCLSGFMGMD IPPPSGPLWI LGDVFIGRYY TVFDRDNNRV GFAEAARL

Spezifität: This antibody gives a positive signal in the following human (Jurkat, HT1080, HUH, MDA-MB-231, ARPE19, SH-SY5Y), canine (MDCK) and monkey (COS-7) whole cell lysates.

Produktmerkmale: Cathepsin D

Aufreinigung: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:250-1:1,000, IF:1:50-1:200, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000, IEM:1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Referenzen für anti-Cathepsin D Antikörper (ABIN6254162)

Pelkonen, Sato, Reinisalo, Kidron, Tachikawa, Watanabe, Uchida, Urtti, Terasaki: "LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line." in: Molecular pharmaceutics, Vol. 14, Issue 3, pp. 605-613, (2017) (PubMed).

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: Cathepsin D

Hintergrund:

Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

ceroid-lipofuscinosis, CLN10, CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody.

Pathways: Peptide Hormone Metabolism