Transferrin Receptor Antikörper (FITC)

Produktnummer ABIN6253930

Der Maus-Monoklonal Anti-Transferrin Receptor-Antikörper wurde für FACS und ICC validiert. Er ist geeignet zum Nachweis von Transferrin Receptor in Proben aus Human. }

Kurzübersicht für Transferrin Receptor Antikörper (FITC) (ABIN6253930)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: DF1513

Produktdetails anti-Transferrin Receptor Antikörper (FITC)

Spezifität: DF1513, produces mouse IgG1 immunoglobulins directed against the transferrin receptor. The transferrin receptor is a type II membrane glycoprotein existing as a homodimer of 180-190 kD with the interchain disulphide bond

Aufreinigung: Ion exchange column

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: immunohistochemistry on cytospots, immunohistochemistry on paraffin imbedded, immunohistochemistry on frozen tissue sections

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: Antigen distribution: Expression of CD71, or the transferrin receptor, is very low on resting leukocytes but is upregulated upon activation reflecting the iron dependence of activation. In other tissues, CD71 is expressed on most dividing cells and also on brain endothelium and alveolar macrophage [1,2]. The ligand is the serum iron transport protein transferrin. DF1513 was clustered at the Leukocyte Typing Workshop IV [5]. Cellular Expression: Activated leukocytes.

Pathways: Transition Metal Ion Homeostasis