Retinoblastoma Protein (Rb) Antikörper
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- Target Alle Retinoblastoma Protein (Rb) (Rb Protein) Antikörper anzeigen
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- A human recombinant protein was used as the immunogen for this Rb antibody.
- Klon
- RB1-1754
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product Rb Protein Primärantikörper
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- Applikationshinweise
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WB: 0.5-1 μg/mL
IP: 1-2 μg/500 μg protein lysate
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Titering of the Rb antibody may be required for optimal performance. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Target
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Andere Bezeichnung
- Retinoblastoma / Rb (Rb Protein Produkte)
- Hintergrund
- Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
- Gen-ID
- 5925
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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