ATG4B Antikörper (N-Term)
Kurzübersicht für ATG4B Antikörper (N-Term) (ABIN6252580)
Target
Alle ATG4B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Aufreinigung
- Protein A affinity chromatography
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Immunogen
- A recombinant protein fragment from the N-terminal region of ATG4B was used as the immunogen for this antibody.
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Isotyp
- IgG
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Applikationshinweise
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Western blot: 4-6 μg/mL
Provided assay concentrations are suggestions only, ATG4B antibody titration may be required for optimal results. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
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Andere Bezeichnung
- ATG4B
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Hintergrund
- Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The 'autophagy-related gene' ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.
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Gen-ID
- 23192
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UniProt
- Q9Y4P1
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Pathways
- Autophagie
Target
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