Nkx2-2 Antikörper

Produktnummer ABIN6252568

Der Kaninchen Polyklonal Anti-Nkx2-2-Antikörper wurde für IF, IHC und FACS validiert. Er ist geeignet, Nkx2-2 in Proben von Human zu detektieren.

Kurzübersicht für Nkx2-2 Antikörper (ABIN6252568)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Nkx2-2 Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml

IF: 1-2 μg/mL

IHC (FFPE): 1-2 μg/mL for 30 minutes at RT

Titering of the NKX2.2 antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: NKX2.2

Hintergrund: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

Gen-ID: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis