TXNIP Antikörper (N-Term)

Produktnummer ABIN6252540

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TXNIP in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TXNIP Antikörper (N-Term) (ABIN6252540)

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TXNIP Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1-3 μg/mL

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu TXNIP

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Andere Bezeichnung: TXNIP

Hintergrund: TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.

Gen-ID: 10628

UniProt: Q9H3M7

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome