MAPKAP1 Antikörper (C-Term)
Kurzübersicht für MAPKAP1 Antikörper (C-Term) (ABIN6252515)
Target
Alle MAPKAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Aufreinigung
- Protein A purified antibody
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Immunogen
- A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
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Isotyp
- IgG
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Applikationshinweise
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Western blot: 1-3 μg/mL
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
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Andere Bezeichnung
- SIN1
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Hintergrund
- MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
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Gen-ID
- 79109
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UniProt
- Q9BPZ7
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Pathways
- PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
Target
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